abstract：OBJECTIVES:Platelet-rich plasma has been used in the treatment of extraction socket; however, randomized controlled clinical trial is still lacking to evaluate its effect on extraction socket healing. MATERIALS AND METHODS:Single center, assessor-blinded, parallel group, randomized controlled clinical trial was conduc...

journal_title：Clinical oral investigations

authors： Anitua E,Murias-Freijo A,Alkhraisat MH,Orive G

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate if a minimally invasive oral health package with the use of atraumatic restorative treatment (ART) or a conventional restorative technique (CT) would result in any perceived benefit from the patients' perspective and if there would be any difference between the two tr...

journal_title：Clinical oral investigations

authors： da Mata C,Cronin M,O'Mahony D,McKenna G,Woods N,Allen PF

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:The purpose of this case series was to evaluate the new bone formation following guided bone regeneration (GBR) with a calcium phosphosilicate (CPS), alloplastic bone putty at peri-implant dehiscence defects and to assess survival rate of implants placed in the augmented sites after 12 months of function. M...

journal_title：Clinical oral investigations

authors： Konstantinidis I,Kumar T,Kher U,Stanitsas PD,Hinrichs JE,Kotsakis GA

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:Conventional prosthesis is generally inapplicable following reconstruction with free fibula flaps (FFF) due to impaired bone and soft tissue conditions, and rehabilitation via enossal implants in FFF is relatively novel. This retrospective study aimed to document the surgical aspects of this option and to de...

journal_title：Clinical oral investigations

authors： Hakim SG,Kimmerle H,Trenkle T,Sieg P,Jacobsen HC

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:The aim of this systematic review was to assess the efficacy of bioactive glass (BG) in bone regeneration for implant site development procedures. MATERIAL AND METHODS:The following specific question was formulated with reference to Population, Intervention, Control, Outcomes (PICO): "In persons that underg...

journal_title：Clinical oral investigations

authors： Ioannou AL,Kotsakis GA,Kumar T,Hinrichs JE,Romanos G

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:This study aims to investigate the bleaching effectiveness of photon-initiated photoacoustic streaming (PIPS) using 35 % hydrogen peroxide on discolored teeth as compared with different devital bleaching techniques. MATERIALS AND METHODS:Fifty extracted human mandibular incisors were collected and artificia...

journal_title：Clinical oral investigations

authors： Arslan H,Akcay M,Yasa B,Hatirli H,Saygili G

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:Azithromycin is a macrolide antibiotic that appears to have both antibacterial and anti-inflammatory properties. This study aimed to investigate the effect of azithromycin on the production of pro-inflammatory cytokines and chemokines by human gingival fibroblasts (HGF) in vitro. MATERIALS AND METHODS:The ef...

journal_title：Clinical oral investigations

authors： Doyle CJ,Fitzsimmons TR,Marchant C,Dharmapatni AA,Hirsch R,Bartold PM

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:The aim of this article is to compare the influence of surface treatment on the integration (at 2, 4 and 8 weeks) of 120 dental implants inserted in 60 tibiae of rabbits. MATERIALS AND METHODS:Four different surfaces were double-blind tested: blasted, acid-etched and discrete crystal deposition (DCD) (group ...

journal_title：Clinical oral investigations

authors： Calvo-Guirado JL,Satorres-Nieto M,Aguilar-Salvatierra A,Delgado-Ruiz RA,Maté-Sánchez de Val JE,Gargallo-Albiol J,Gómez-Moreno G,Romanos GE

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:It is well accepted that stage-specific embryonic antigen (SSEA)-4 is an antigen that is useful to isolate adult stem cells analogous to embryonic stem cells. Therefore, in the present study, we investigated whether SSEA-4 can also be used as a marker to identify human deciduous dental pulp (D-DP) stem cells...

journal_title：Clinical oral investigations

authors： Kawanabe N,Fukushima H,Ishihara Y,Yanagita T,Kurosaka H,Yamashiro T

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:Root canal treatment failures often correlate with persistent biomaterial-associated endodontic infections. The aim of the present study was to assess the impact of endodontic obturation material sampling from root canals with posttreatment apical periodontitis on improving standard study protocols. MATERIA...

journal_title：Clinical oral investigations

authors： Karygianni L,Anderson AC,Tennert C,Kollmar K,Altenburger MJ,Hellwig E,Al-Ahmad A

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:Candida albicans is a common fungal infection and is commensal in 40-65 % of healthy adults. The development and pharmacokinetics of a novel sustained release clotrimazole varnish (Clot-SRV) for topical oral use have been reported. The aim of this study was to compare the efficacy of this varnish with clotri...

journal_title：Clinical oral investigations

authors： Czerninski R,Pikovsky A,Gati I,Friedman M,Steinberg D

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:This study investigated toothbrush abrasion and in vitro aging on ceramic (indirect technique) and composite veneers (direct technique). MATERIALS AND METHODS:Identical composite and individual human incisors were restored with industrially preformed composite veneers, indirectly produced ceramic veneers, a...

journal_title：Clinical oral investigations

authors： Rosentritt M,Sawaljanow A,Behr M,Kolbeck C,Preis V

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate repair after endodontic surgery using two- and tridimensional imaging methods. MATERIALS AND METHODS:Periapical radiographs and cone beam computed tomography (CBCT) were performed before the surgeries and after 48 h (baseline), 4 months, and 8 months. The area (square mi...

journal_title：Clinical oral investigations

authors： Tanomaru-FIlho M,Jorge ÉG,Guerreiro-Tanomaru JM,Reis JM,Spin-Neto R,Gonçalves M

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study is to compare wound healing and patient pain perception of single-incision (single-incision, modified single-incision) and trap-door surgical techniques to harvest subepithelial connective tissue grafts from the palate. MATERIAL AND METHODS:Thirty-six patients were selected for root co...

journal_title：Clinical oral investigations

authors： Fickl S,Fischer KR,Jockel-Schneider Y,Stappert CF,Schlagenhauf U,Kebschull M

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:Lithium disilicate can easily be machined by CAM techniques in its metasilicate status. Due to slightly inferior material properties, the material is not yet recommended for three-unit fixed dental prosthesis (FDP) as it is the case for the press material up to the second bicuspid. Therefore, the aim of this...

journal_title：Clinical oral investigations

authors： Reich S,Endres L,Weber C,Wiedhahn K,Neumann P,Schneider O,Rafai N,Wolfart S

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the effect of daily exposure to a denture cleanser on a multispecies biofilm. MATERIALS AND METHODS:Multispecies biofilms (five bacteria and Candida albicans) were developed for 64.5 h on acrylic resin specimens and randomized into control and experimental groups. In the...

journal_title：Clinical oral investigations

authors： Lucena-Ferreira SC,Ricomini-Filho AP,Silva WJ,Cury JA,Cury AA

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate and compare the osteoblastic differentiation ability of dedifferentiated fat (DFAT) cells and adipose stem cells (ASCs) from the buccal fat pad (BFP). MATERIALS AND METHODS:We isolated human DFAT cells and ASCs from the BFP of a patient who underwent oral and maxill...

journal_title：Clinical oral investigations

authors： Kishimoto N,Momota Y,Hashimoto Y,Tatsumi S,Ando K,Omasa T,Kotani J

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to quantify the blue light that passes through different incremental thicknesses of bulk fill in comparison to conventional resin-based composites (RBCs) and to relate it to the induced mechanical properties. MATERIALS AND METHODS:Seven bulk fill, five nanohybrid and two flowable R...

journal_title：Clinical oral investigations

authors： Bucuta S,Ilie N

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the contamination level of toothbrushes by mutans streptococci (MS) and the efficacy of antimicrobial solutions: cetylpyridinium chloride 0.05 % (CPC; Cepacol™) and chlorhexidine 0.12 % (CHX; Periogard™), to disinfect toothbrushes of preschool-aged children in day-care centers. MATERIAL AND METHO...

journal_title：Clinical oral investigations

authors： Nelson-Filho P,Pereira MS,De Rossi A,da Silva RA,de Mesquita KS,de Queiroz AM,da Silva LA

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:Root resorptions due to a reduced repair function of cementoblasts are common side effects during orthodontic tooth movement (OTM). The mechanisms, which lead to an impaired cementoblast function, are not fully understood. Therefore, we aimed to investigate changes in the gene expression of cementoblasts dur...

journal_title：Clinical oral investigations

authors： Diercke K,Zingler S,Kohl A,Lux CJ,Erber R

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:Symptoms of temporomandibular joint (TMJ) dysfunction can seriously compromise patients' quality of life. The aim of our study was to use magnetic resonance imaging (MRI) T2 mapping of the articular disc to determine whether T2 mapping of the TMJ disc is feasible in routine clinical imaging and to assess the...

journal_title：Clinical oral investigations

authors： Schmid-Schwap M,Bristela M,Pittschieler E,Skolka A,Szomolanyi P,Weber M,Piehslinger E,Trattnig S

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to compare temperature variation during osteotomies with trephine drills under different irrigation conditions: without irrigation, external irrigation, and double irrigation. MATERIALS AND METHODS:Synthetic blocks of bone (type I density) were used for drilling procedures with ...

journal_title：Clinical oral investigations

authors： Gehrke SA,Pazetto MK,de Oliveira S,Corbella S,Taschieri S,Mardegan FE

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:The present longitudinal study aimed to compare changes in the lower third molar position and nerve involvement in orthodontically treated patients with and without premolar extractions. MATERIALS AND METHODS:The sample consisted of pretreatment and posttreatment panoramic radiographs of 349 orthodontically...

journal_title：Clinical oral investigations

authors： Miclotte A,Van Hevele J,Roels A,Elaut J,Willems G,Politis C,Jacobs R

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Several studies have shown the possible involvement of Helicobacter pylori infection in individuals with recurrent aphthous stomatitis (RAS), but the relationship remains controversial. This meta-analysis was performed to validate the association between RAS and H. pylori infection. MATERIALS AND METHODS:Th...

journal_title：Clinical oral investigations

authors： Li L,Gu H,Zhang G

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Reconstruction of large and complex bone segments is a challenging problem facing maxillofacial surgery. The majority of current regenerative approaches rely on extrinsic vascularization, which is deficient after cancer ablation and irradiation. The aim of the study was to investigate the efficacy of intrinsi...

journal_title：Clinical oral investigations

authors： Eweida AM,Nabawi AS,Abouarab M,Kayed M,Elhammady H,Etaby A,Khalil MR,Shawky MS,Kneser U,Horch RE,Nagy N,Marei MK

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to analyze the porosity of three photopolymerizable resin composites: one high-viscous resin composite (Filtek™ P60®, 3 M™ ESPE™), one moderate-viscosity resin composite (Grandio®, VOCO™), and one low-viscous resin composite (Filtek™ Supreme XTE®, 3 M™ ESPE™). MATERIALS AND METHODS...

journal_title：Clinical oral investigations

authors： Balthazard R,Jager S,Dahoun A,Gerdolle D,Engels-Deutsch M,Mortier E

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVES:Emdogain, containing an extract of fetal porcine enamel matrix proteins, is a potent stimulator of in vitro osteoclastogenesis. The underlying molecular mechanisms are, however, unclear. MATERIAL AND METHODS:Here, we have addressed the role of transforming growth factor-beta receptor type 1 (TGF-βRI) kinase...

journal_title：Clinical oral investigations

authors： Gruber R,Roos G,Caballé-Serrano J,Miron R,Bosshardt DD,Sculean A

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to introduce a novel three-dimensional (3D) method to quantify the relative amount of different tissue components in bone substitute-treated defects by means of integration of confocal laser imaging into micro-computed tomography (μCT) analysis. MATERIALS AND METHODS:One standardize...

journal_title：Clinical oral investigations

authors： Clozza E,Obrecht M,Dard M,Coelho PG,Dahlin C,Engebretson SP

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:The main goal of the present study was to compare the biomechanical stability of locking plates and conventional miniplate combinations in human mandibles reconstructed with fibular grafts. MATERIALS AND METHODS:A specially developed and well-proven testing device reproduced the in vivo loading conditions o...

journal_title：Clinical oral investigations

authors： Trainotti S,Raith S,Kesting M,Eichhorn S,Bauer F,Kolk A,Lethaus B,Hölzle F,Steiner T

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare the push-out bond strength of three calcium silicate cements to dentine after two different irrigation regimes. MATERIALS AND METHODS:One hundred eighty 2-mm-thick root sections were prepared. The sections were divided into three main groups (n = 60). In group A, the sec...

journal_title：Clinical oral investigations

authors： Çelik D,Er K,Serper A,Taşdemir T,Ceyhanlı KT

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:This study aimed to compare (18)F-fluorodesoxyglucose positron emission tomography/MRI ((18)F-FDG-PET-MRI) fusion images, including diffusion-weighted imaging (DWI), (18)F-FDG-PET/CT, and ultrasound (US) regarding their performance in nodal staging of patients with head and neck squamous cell carcinoma (HNSCC...

journal_title：Clinical oral investigations

authors： Heusch P,Sproll C,Buchbender C,Rieser E,Terjung J,Antke C,Boeck I,Macht S,Scherer A,Antoch G,Heusner TA,Handschel J

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:The combination of sodium hypochlorite (NaOCl) and chlorhexidine (CHX) yields a "precipitate potentially toxic" (PPT). The aim of this study was to evaluate the tissue response to implanted polyethylene tubes filled with PPT-soaked fibrin sponge. METHODS:Forty rats received four polyethylene tubes each; eac...

journal_title：Clinical oral investigations

authors： Cintra LT,Watanabe S,Samuel RO,da Silva Facundo AC,de Azevedo Queiroz IO,Dezan-Júnior E,Gomes-Filho JE

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:The aim of this comprehensive literature review is to provide recommendations and guidelines for dental implant therapy in patients with a history of radiation in the head and neck region. For the first time, a meta-analysis comparing the implant survival in irradiated and non-irradiated patients was perform...

journal_title：Clinical oral investigations

authors： Schiegnitz E,Al-Nawas B,Kämmerer PW,Grötz KA

更新日期：2014-04-01 00:00:00

abstract：AIMS:The aims of this double-blind, controlled, crossover study were to assess the influence of food preservatives on in situ dental biofilm growth and vitality, and to evaluate their influence on the ability of dental biofilm to demineralize underlying enamel over a period of 14 days. MATERIALS AND METHODS:Twenty vol...

journal_title：Clinical oral investigations

authors： Arweiler NB,Netuschil L,Beier D,Grunert S,Heumann C,Altenburger MJ,Sculean A,Nagy K,Al-Ahmad A,Auschill TM

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to determine the prevalence of permanent first molar (P1M) extraction among Turkish adolescents and young adult subpopulation, and to investigate the effects of P1M extraction on development of the third molars (3Ms) in the same quadrant. MATERIALS AND METHODS:A retrospectiv...

journal_title：Clinical oral investigations

authors： Halicioglu K,Toptas O,Akkas I,Celikoglu M

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:Most patients with bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) report a previous tooth extraction at the necrosis site before the diagnosis was made. At older ages, most teeth are extracted due to periodontal disease, which is per se another BP-ONJ trigger factor. The aim of this study was t...

journal_title：Clinical oral investigations

authors： Walter C,Laux C,Sagheb K

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess whether and how the information obtained by means of cone beam computed tomography (CBCT) on maxillary posterior teeth differs from that obtained by panoramic radiography. MATERIALS AND METHOD:From 157 subjects (mean age 48 years, range 19-84 years; 89 females) referre...

journal_title：Clinical oral investigations

authors： Shahbazian M,Vandewoude C,Wyatt J,Jacobs R

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:Noninvasive optical methods such as photoplethysmography, established for blood pulse detection in organs, have been proposed for vitality testing of human dental pulp. However, no information is available on the mechanism of action in a closed pulp chamber and on the impairing influence of other than pulpal ...

journal_title：Clinical oral investigations

authors： Niklas A,Hiller KA,Jaeger A,Brandt M,Putzger J,Ermer C,Schulz I,Monkman G,Giglberger S,Hirmer M,Danilov S,Ganichev S,Schmalz G

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:The present study aims to investigate the relevance of immunohistochemical p53 expression in carcinomas of the oral cavity and of the head and neck region. Long-term clinical and histopathological follow-up findings as well as HPV status are correlated with the results of this examination. MATERIALS AND MET...

journal_title：Clinical oral investigations

authors： Gröbe A,Hanken H,Al-Dam A,Cachovan G,Smeets R,Krohn A,Clauditz T,Grob T,Simon R,Sauter G,Kluwe L,Heiland M,Blessmann M

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:This study aims to evaluate the effect of a minimally invasive mesial-occlusal-distal (mod) preparation on the marginal adaptation of ceramic and composite inlays with the aim of saving sound dental substance. MATERIALS AND METHODS:Class II mod cavities were prepared in 50 extracted human molars and randoml...

journal_title：Clinical oral investigations

authors： Zaruba M,Kasper R,Kazama R,Wegehaupt FJ,Ender A,Attin T,Mehl A

更新日期：2014-01-01 00:00:00